Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | BRS3 | P32247 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841940 | 0.84 | KDM4C (0.58) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL11836193 | 0.82 | KDM4E (0.42) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL4428237 | 0.82 | KDM4E (0.50) | KDM4EKDM5AKDM5BBRS3DAO | |
| SCHEMBL3912930 | 0.82 | KDM4E (0.53) | KDM4ESMN1; SMN2KDM5AKDM5BBRS3 | |
| SCHEMBL3917621 | 0.81 | DAO (0.46) | KDM4EKDM5AKDM5BBRS3DAO | |
| SCHEMBL3920671 | 0.81 | DAO (0.54) | KDM4EALDH1A1GAASMN1; SMN2KDM5B | |
| SCHEMBL4430485 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL4428346 | 0.80 | CAPN1 (0.42) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL4433258 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL11836096 | 0.78 | DAO (0.52) | ALDH1A1SMN1; SMN2KDM5AKDM5BERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948903-A | Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins | PARKE, DAVIS & COMPANY (US) | 1976-04-06 | — | — | US | disclosed |