Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826408 | 0.77 | MAPT (0.39) | CASP1MAPTALDH1A1S1PR2LMNA | |
| SCHEMBL13525199 | 0.77 | PABPC1 (0.41) | MAPTALDH1A1RAB9AS1PR2LMNA | |
| SCHEMBL11828101 | 0.75 | PLK1 (0.34) | MAPTALDH1A1RAB9AS1PR2LMNA | |
| SCHEMBL11823825 | 0.74 | CASP1 (0.38) | CASP1MAPTALDH1A1RAB9ALMNA | |
| SCHEMBL11822154 | 0.74 | MEN1 (0.37) | MAPTALDH1A1RAB9AS1PR2LMNA | |
| SCHEMBL11326616 | 0.73 | ALDH1A1 (0.37) | MAPTALDH1A1RAB9ALMNATDP1 | |
| SCHEMBL11827715 | 0.72 | PLK1 (0.34) | MAPTALDH1A1RAB9AS1PR2LMNA | |
| SCHEMBL11648128 | 0.69 | ALDH1A1 (0.35) | CASP1MAPTALDH1A1TDP1CYP3A4 | |
| SCHEMBL13371734 | 0.69 | SIGMAR1 (0.36) | MAPTALDH1A1RAB9ACYP3A4SMN1; SMN2 | |
| SCHEMBL1153853 | 0.68 | CYP3A4 (0.38) | MAPTALDH1A1RAB9ALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984402-A | Indoanilines for dyeing keratinous fibers | L'OREAL (FR) | 1976-10-05 | — | — | US | claimed |
| US-3984402-A | Indoanilines for dyeing keratinous fibers | L'OREAL (FR) | 1976-10-05 | — | — | US | disclosed |