Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11824409 | 0.90 | ADAMTS4 (0.46) | ADAMTS4ALDH1A1TDP1CYP1A2AKR1C3 | |
| SCHEMBL11672909 | 0.81 | ALDH1A1 (0.60) | ADAMTS4ALDH1A1TDP1CYP1A2AKR1C3 | |
| SCHEMBL11837933 | 0.80 | MMP1 (0.50) | ALDH1A1AKR1C3AKR1C2MEN1MAPT | |
| SCHEMBL11842494 | 0.80 | ALDH1A1 (0.62) | ADAMTS4ALDH1A1TDP1CYP1A2TSHR | |
| SCHEMBL14494913 | 0.80 | ALDH1A1 (0.61) | ADAMTS4ALDH1A1TDP1CYP1A2MEN1 | |
| SCHEMBL11836259 | 0.79 | AKR1C3 (0.46) | CYP1A2AKR1C3AKR1C2TSHRPTGS2 | |
| SCHEMBL11827232 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP1A2AKR1C3AKR1C2TSHR | |
| SCHEMBL11833643 | 0.78 | ALDH1A1 (0.51) | ADAMTS4ALDH1A1TDP1CYP1A2TSHR | |
| SCHEMBL11837592 | 0.77 | ALDH1A1 (0.54) | ADAMTS4ALDH1A1TDP1CYP1A2TSHR | |
| SCHEMBL13291829 | 0.76 | ALDH1A1 (0.65) | ADAMTS4ALDH1A1TDP1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |