Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837700 | 0.86 | PTGS2 (0.46) | ALDH1A1MAPK1TRPA1PTGS2PTGS1 | |
| SCHEMBL11836259 | 0.83 | AKR1C3 (0.46) | TRPA1PTGS2PTGS1KMT2AMEN1 | |
| SCHEMBL11832975 | 0.81 | MMP2 (0.48) | PTGS2CYP1A2GRIA4 | |
| SCHEMBL6632227 | 0.80 | TRPA1 (0.55) | MAPK1TRPA1LMNAFFAR1 | |
| SCHEMBL6628032 | 0.80 | TRPA1 (0.55) | MAPK1TRPA1LMNAFFAR1 | |
| SCHEMBL5475206 | 0.80 | TRPA1 (0.55) | MAPK1TRPA1LMNAFFAR1 | |
| SCHEMBL11835910 | 0.79 | ADAMTS4 (0.55) | ALDH1A1PTGS2KMT2AMEN1AKR1C3 | |
| SCHEMBL11841932 | 0.77 | LMNA (0.57) | ALDH1A1MAPK1PTGS2PTGS1KMT2A | |
| SCHEMBL11829363 | 0.75 | USP5 (0.44) | MAPK1TRPA1PTGS2PTGS1AKR1C3 | |
| SCHEMBL11829051 | 0.75 | PTGS2 (0.46) | PTGS2PTGS1KMT2AMEN1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |