Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | RAD52 | P43351 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841247 | 0.89 | KDM4E (0.68) | MEN1KMT2AKDM4ERAD52POLB | |
| SCHEMBL11838114 | 0.85 | KDM4E (0.67) | KDM4ERAD52POLBRXFP1LMNA | |
| SCHEMBL11811501 | 0.82 | MEN1 (0.50) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11834897 | 0.81 | KDM4E (0.76) | MEN1KMT2AKDM4ERAD52POLB | |
| SCHEMBL11848412 | 0.81 | KDM4E (0.68) | MEN1KMT2AKDM4ERAD52POLB | |
| SCHEMBL12413492 | 0.77 | KDM4E (0.66) | MEN1KMT2AKDM4ERAD52POLB | |
| SCHEMBL11623083 | 0.77 | HEXA (0.74) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6272682 | 0.76 | MAPT (0.73) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11835734 | 0.76 | KDM4E (0.65) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11632652 | 0.76 | NPSR1 (0.67) | KDM4ERAD52POLBRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |