Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 7/20 | 0.63 |
| ▸ | DRD2 | P14416 | 7/20 | 0.63 |
| ▸ | HTR2A | P28223 | 6/20 | 0.63 |
| ▸ | HTR6 | P50406 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632287 | 0.86 | HTR7 (0.70) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11631848 | 0.85 | KDM4E (0.86) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11630456 | 0.85 | HTR1A (0.71) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11631571 | 0.85 | HTR1A (0.85) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11848610 | 0.81 | KDM4E (0.64) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11629079 | 0.81 | L3MBTL1 (0.51) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11842208 | 0.81 | KDM4E (0.61) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11631929 | 0.79 | HTR7 (0.82) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11843159 | 0.79 | HTR1A (0.80) | KDM4ELMNAMAPK1HTR1ADRD2 | |
| SCHEMBL11838777 | 0.78 | HTR7 (0.84) | KDM4ELMNAMAPK1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |