Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912930 | 0.76 | KDM4E (0.53) | KDM4ESMN1; SMN2KDM4CPARP1NAPRT | |
| SCHEMBL11835340 | 0.75 | ADRA1D (0.42) | CYP2C9KDM4ESMN1; SMN2ADRA1DPNP | |
| SCHEMBL4428237 | 0.74 | KDM4E (0.50) | KDM4EKDM4CPARP1 | |
| SCHEMBL11835298 | 0.73 | KDM4E (0.43) | KDM4EKDM4CPNPPOLBTDP1 | |
| SCHEMBL5538742 | 0.72 | HPGD (0.46) | CYP2C9KDM4ESMN1; SMN2CYP2C19ADRA1D | |
| SCHEMBL4433258 | 0.72 | KDM4E (0.55) | KDM4ESMN1; SMN2KDM4CHPGD | |
| SCHEMBL4432530 | 0.72 | KDM4E (0.47) | KDM4EKDM4C | |
| SCHEMBL4428820 | 0.72 | KDM4E (0.47) | KDM4ESMN1; SMN2POLBNAPRT | |
| SCHEMBL11835838 | 0.71 | KDM4E (0.58) | KDM4ESMN1; SMN2PARP1HPGD | |
| SCHEMBL11836193 | 0.71 | KDM4E (0.42) | KDM4ESMN1; SMN2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960980-A | Method of producing elastomer resins | BRIDGESTONE TIRE COMPANY LIMITED (JA) | 1976-06-01 | — | — | US | claimed |
| US-3948903-A | Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins | PARKE, DAVIS & COMPANY (US) | 1976-04-06 | — | — | US | disclosed |