Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR6 | P50406 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HEXA | P06865 | 1/20 | 0.55 |
| ▸ | HEXB | P07686 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632652 | 0.82 | NPSR1 (0.67) | RAD52KDM4EPOLBALDH1A1LMNA | |
| SCHEMBL11633309 | 0.81 | RAD52 (0.49) | RAD52KDM4EPOLBALDH1A1HTR1A | |
| SCHEMBL11434790 | 0.81 | RAD52 (1.00) | RAD52KDM4EPOLBALDH1A1HTR1A | |
| SCHEMBL11631571 | 0.81 | HTR1A (0.85) | RAD52KDM4EPOLBALDH1A1HTR1A | |
| SCHEMBL11830608 | 0.79 | KDM4E (0.59) | RAD52KDM4EPOLBALDH1A1HTR1A | |
| SCHEMBL11838190 | 0.76 | HTR1A (0.54) | RAD52KDM4EPOLBALDH1A1HTR1A | |
| SCHEMBL11632693 | 0.75 | DRD2 (0.88) | KDM4EALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL11623083 | 0.75 | HEXA (0.74) | RAD52KDM4EPOLBALDH1A1KMT2A | |
| SCHEMBL6272682 | 0.75 | MAPT (0.73) | RAD52KDM4EPOLBALDH1A1KMT2A | |
| SCHEMBL11834897 | 0.74 | KDM4E (0.76) | RAD52KDM4EPOLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |