Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635081 | 0.85 | L3MBTL1 (0.56) | RAD52L3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL11631256 | 0.83 | HTR1A (0.62) | L3MBTL1KDM4EALDH1A1POLBHTR1A | |
| SCHEMBL11631244 | 0.82 | L3MBTL1 (0.50) | RAD52L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL11630716 | 0.82 | RAD52 (0.43) | RAD52L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL11837583 | 0.81 | RAD52 (0.69) | RAD52KDM4EALDH1A1POLBHTR1A | |
| SCHEMBL11636284 | 0.79 | DRD2 (0.63) | KDM4EALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL11629077 | 0.79 | L3MBTL1 (0.56) | RAD52L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL11633867 | 0.77 | L3MBTL1 (0.54) | RAD52L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL11631804 | 0.77 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HTR1ADRD2 | |
| SCHEMBL11629079 | 0.77 | L3MBTL1 (0.51) | RAD52L3MBTL1KDM4EPOLBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4007191-A | ANTIDEPRESSANT | E. R. SQUIBB & SONS, INC. (US) | 1977-02-08 | — | — | US | disclosed |