Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847293 | 0.87 | MEN1 (0.43) | LMNATDP1ALDH1A1MAPTPTGS2 | |
| SCHEMBL11850461 | 0.85 | PTGS2 (0.47) | LMNAALDH1A1MAPTPTGS2MMP8 | |
| SCHEMBL11851821 | 0.85 | CA12 (0.47) | LMNATDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11838414 | 0.85 | MAPT (0.51) | LMNATDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11841432 | 0.84 | LMNA (0.38) | LMNATDP1ALDH1A1MAPTPTGS2 | |
| SCHEMBL11834068 | 0.84 | LMNA (0.49) | LMNATDP1ALDH1A1MAPTPTGS2 | |
| SCHEMBL11842204 | 0.84 | HTT (0.46) | LMNATDP1ALDH1A1MAPTMMP8 | |
| SCHEMBL11840175 | 0.84 | MAPT (0.43) | LMNATDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11837938 | 0.83 | POLB (0.47) | LMNATDP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11835459 | 0.82 | PTGS2 (0.37) | LMNATDP1ALDH1A1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |