Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3801842 | 0.95 | MAPT (0.46) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL11847293 | 0.87 | MEN1 (0.43) | MAPTMEN1KMT2ALMNAFFAR1 | |
| SCHEMBL11850461 | 0.85 | PTGS2 (0.47) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL11838414 | 0.85 | MAPT (0.51) | MAPTCYP1A2LMNAFFAR1RAB9A | |
| SCHEMBL11851821 | 0.85 | CA12 (0.47) | MAPTKMT2ACYP1A2LMNACYP2C9 | |
| SCHEMBL10781702 | 0.84 | PTGS2 (0.45) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL11848073 | 0.84 | LMNA (0.38) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL11841432 | 0.84 | LMNA (0.38) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL11834068 | 0.84 | LMNA (0.49) | MAPTMEN1KMT2ACYP1A2LMNA | |
| SCHEMBL11842204 | 0.84 | HTT (0.46) | MAPTNPSR1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |