Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | F2 | P00734 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407617 | 0.87 | ENPP2 (0.62) | MEN1KMT2AMAPTGAABCHE | |
| SCHEMBL11838896 | 0.85 | MAPT (0.84) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL8082984 | 0.84 | MAPT (0.82) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL17602198 | 0.82 | MAPT (0.62) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL855509 | 0.82 | MAPT (0.65) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL4667164 | 0.81 | MAPT (1.00) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL17609131 | 0.81 | MAPT (0.64) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL3720530 | 0.80 | MEN1 (0.76) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL1844630 | 0.80 | MAPT (0.70) | MEN1KMT2AMAPTGAABLM | |
| SCHEMBL17602316 | 0.79 | BCHE (0.64) | MEN1KMT2AMAPTGAABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193601-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044429-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |