Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845184 | 0.80 | CDC25B (0.47) | POLBCA12CA1CA2CA9 | |
| SCHEMBL11851310 | 0.79 | POLB (0.48) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL16581035 | 0.76 | LMNA (0.51) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL2883308 | 0.76 | HCAR3 (0.55) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL2879281 | 0.76 | MAPT (0.48) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL573640 | 0.76 | KDM4E (0.58) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL573259 | 0.75 | ALDH1A1 (0.57) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL2876091 | 0.75 | LMNA (0.46) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL13283938 | 0.75 | LMNA (0.46) | POLBKMT2AMEN1CA12CA1 | |
| SCHEMBL31108456 | 0.75 | ALDH1A1 (0.57) | POLBKMT2AMEN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |