Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11827510 | 0.82 | CSNK2A1 (0.51) | CSNK2A1MMP2MMP3PTGES2RORC | |
| SCHEMBL11827986 | 0.82 | SLC13A5 (0.51) | MMP2SLC13A5FFAR1 | |
| SCHEMBL11829438 | 0.78 | P2RX3 (0.37) | — | |
| SCHEMBL11827800 | 0.76 | THRB (0.37) | — | |
| SCHEMBL11802733 | 0.75 | CSNK2A1 (0.55) | CSNK2A1RORCHCAR2ADRB1ADRB3 | |
| SCHEMBL11836371 | 0.75 | CSNK2A1 (0.46) | CSNK2A1MMP2MMP3PTGES2RORC | |
| SCHEMBL28553472 | 0.71 | MTNR1A (0.51) | CSNK2A1PTGES2RORCCD274SHMT1 | |
| SCHEMBL19567203 | 0.70 | CSNK2A1 (0.64) | CSNK2A1RORCHCAR2 | |
| SCHEMBL10952521 | 0.69 | GGPS1 (0.41) | PTGES2SHMT1 | |
| SCHEMBL20781840 | 0.69 | CSNK2A1 (0.62) | CSNK2A1MMP2MMP3PTGES2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |