Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 11/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842846 | 0.78 | CSNK2A1 (0.45) | — | |
| SCHEMBL11826817 | 0.76 | P2RX3 (0.38) | P2RX3AKR1C2AKR1C1 | |
| SCHEMBL11827800 | 0.75 | THRB (0.37) | — | |
| SCHEMBL11829349 | 0.71 | ATM (0.40) | P2RX3AKR1C2AKR1C1 | |
| SCHEMBL11827986 | 0.71 | SLC13A5 (0.51) | — | |
| SCHEMBL11831274 | 0.70 | GABRA1 (0.39) | P2RX3AKR1C2AKR1C1HDAC8ACLY | |
| SCHEMBL11823310 | 0.70 | P2RX3 (0.41) | P2RX3AKR1C2AKR1C1HDAC8 | |
| SCHEMBL27323428 | 0.69 | GABRA1 (0.55) | AKR1C2AKR1C1 | |
| SCHEMBL11831094 | 0.67 | GABRA1 (0.41) | P2RX3AKR1C2AKR1C1 | |
| SCHEMBL4885851 | 0.65 | FPR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |