Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | PDE6D | O43924 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202042 | 0.64 | ALDH1A1 (0.41) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL18153203 | 0.64 | HTR2A (0.44) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL11717879 | 0.63 | HTR2C (0.58) | HTR2AHTR2CHTR2BALDH1A1GAA | |
| SCHEMBL15265044 | 0.62 | ALDH1A1 (0.56) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11716040 | 0.62 | HTR2C (0.56) | HTR2AHTR2CHTR2BALDH1A1GAA | |
| SCHEMBL17076613 | 0.62 | ALDH1A1 (0.33) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL13704044 | 0.62 | GPR3 (0.60) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL28491293 | 0.62 | ALDH1A1 (0.39) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL22792110 | 0.62 | GPR3 (0.60) | HTR2AHTR2CHTR2BALDH1A1LMNA | |
| SCHEMBL13704120 | 0.62 | GPR3 (0.60) | HTR2AHTR2CHTR2BALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994920-A | APPETITE SUPPRESSANT, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |