Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838980 | 0.88 | ALDH1A1 (0.47) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL11843466 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL11788072 | 0.86 | ALDH1A1 (0.64) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL11802821 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL11781725 | 0.81 | GAA (0.43) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL11796927 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL19300067 | 0.74 | ALDH1A1 (0.61) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL11842089 | 0.74 | LMNA (0.51) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL10222974 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CA2LMNAHPGDTSHR | |
| SCHEMBL13283830 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CA2LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939267-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |