Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | AQP1 | P29972 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844329 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11842089 | 0.86 | LMNA (0.51) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11850838 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11789242 | 0.84 | CA2 (0.71) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11843998 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11803735 | 0.81 | CA2 (0.63) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11848504 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11849556 | 0.79 | CA2 (0.67) | ALDH1A1HPGDHSD17B10KDM4EUSP2 | |
| SCHEMBL11780992 | 0.78 | L3MBTL1 (0.41) | ALDH1A1HPGDHSD17B10KDM4EBLM | |
| SCHEMBL11849257 | 0.78 | CA2 (0.63) | ALDH1A1HPGDHSD17B10KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939267-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |