Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11838980 | 0.84 | ALDH1A1 (0.47) | ALDH1A1APPKDM4ELMNAUSP2 | |
| SCHEMBL11788072 | 0.79 | ALDH1A1 (0.64) | ALDH1A1APPKDM4ELMNAUSP2 | |
| SCHEMBL11843998 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAUSP2HSD17B10 | |
| SCHEMBL11802821 | 0.78 | ALDH1A1 (0.56) | ALDH1A1APPKDM4ELMNAUSP2 | |
| SCHEMBL11844329 | 0.77 | ALDH1A1 (0.48) | ALDH1A1APPKDM4ELMNAUSP2 | |
| SCHEMBL11780923 | 0.77 | ALDH1A1 (0.51) | ALDH1A1APPKDM4ELMNAUSP2 | |
| SCHEMBL11798775 | 0.77 | ALDH1A1 (0.48) | ALDH1A1APPKDM4ELMNAUSP2 | |
| SCHEMBL11808102 | 0.77 | CA2 (0.61) | ALDH1A1KDM4ELMNAUSP2HSD17B10 | |
| SCHEMBL11799270 | 0.76 | CA1 (0.43) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL11777201 | 0.75 | GAA (0.45) | ALDH1A1APPLMNAUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992440-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3982018-A | DIURETICS | CIBA-GEIGY CORPORATION (US) | 1976-09-21 | — | — | US | disclosed |
| US-3939267-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |