Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843915 | 0.85 | GRIA2 (0.42) | GRIA2GRIA4ALDH1A1NPSR1LMNA | |
| SCHEMBL11837622 | 0.83 | PPARG (0.45) | GRIA2GRIA4ALDH1A1NPSR1LMNA | |
| SCHEMBL11836185 | 0.82 | GRM6 (0.42) | GRIA2GRIA4ALDH1A1NPSR1MMP8 | |
| SCHEMBL11844271 | 0.82 | MMP8 (0.38) | ALDH1A1NPSR1LMNATSHRPTPN1 | |
| SCHEMBL11841890 | 0.82 | ALDH1A1 (0.41) | ALDH1A1NPSR1LMNATSHRMMP8 | |
| SCHEMBL11843289 | 0.82 | GRIA2 (0.40) | GRIA2GRIA4ALDH1A1NPSR1LMNA | |
| SCHEMBL11839973 | 0.81 | MMP8 (0.40) | ALDH1A1NPSR1LMNATSHRPTPN1 | |
| SCHEMBL11836053 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NPSR1LMNAMMP8SMN1; SMN2 | |
| SCHEMBL11846829 | 0.81 | MEN1 (0.38) | ALDH1A1NPSR1LMNATSHRPTPN1 | |
| SCHEMBL11849305 | 0.81 | GRIA4 (0.46) | GRIA4ALDH1A1NPSR1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |