Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842570 | 0.85 | CA12 (0.44) | PTGS2KMT2AMEN1MAPTHPGD | |
| SCHEMBL11849937 | 0.83 | LMNA (0.52) | GRIA2GRIA4PTGS2KMT2AMEN1 | |
| SCHEMBL11844401 | 0.82 | GRIA2 (0.39) | GRIA2GRIA4KMT2AMEN1MAPT | |
| SCHEMBL11846562 | 0.80 | PPARG (0.49) | PTGS2KMT2AMEN1MAPTHPGD | |
| SCHEMBL11837769 | 0.78 | PTGS2 (0.41) | GRIA2GRIA4PTGS2KMT2AMEN1 | |
| SCHEMBL11844907 | 0.78 | HPGD (0.53) | PTGS2KMT2AMEN1MAPTHPGD | |
| SCHEMBL11788735 | 0.78 | CYP2A6 (0.53) | PTGS2KMT2AMEN1MAPTHPGD | |
| SCHEMBL11838674 | 0.78 | PTGS2 (0.41) | PTGS2KMT2AMEN1MAPTHPGD | |
| SCHEMBL11793687 | 0.76 | ALDH1A1 (0.52) | PTGS2KMT2AMEN1MAPTHPGD | |
| SCHEMBL11841900 | 0.76 | PTGS2 (0.40) | PTGS2KMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |