Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837622 | 0.86 | PPARG (0.45) | MEN1KMT2AALDH1A1KDM4EMMP8 | |
| SCHEMBL11836185 | 0.84 | GRM6 (0.42) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11841890 | 0.84 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11844271 | 0.84 | MMP8 (0.38) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11849305 | 0.83 | GRIA4 (0.46) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11839973 | 0.83 | MMP8 (0.40) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11836053 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11839187 | 0.82 | PPARG (0.46) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11850461 | 0.82 | PTGS2 (0.47) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL11844401 | 0.81 | GRIA2 (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |