Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13903470 | 0.73 | KDM5A (0.46) | KDM5AKDM4CDYRK1ADAPK3ROCK2 | |
| SCHEMBL28380264 | 0.72 | MAPK1 (0.48) | KDM5AKDM4CDYRK1AAURKACDK1 | |
| SCHEMBL16593421 | 0.72 | KDM5A (0.45) | KDM5AKDM4CDYRK1AAURKACDK2 | |
| SCHEMBL4364047 | 0.71 | KDM4E (0.49) | MAPK1 | |
| SCHEMBL27595634 | 0.70 | KDM5A (0.47) | KDM5AKDM4CDYRK1ADAPK3ROCK2 | |
| SCHEMBL7743849 | 0.69 | MAPK1 (0.50) | DYRK1AAURKADAPK3JAK2ROCK2 | |
| SCHEMBL22766344 | 0.69 | PSMD14 (0.44) | MAPK1KDRGSK3BPRKD2 | |
| SCHEMBL27595486 | 0.68 | KDM5A (0.45) | KDM5AKDM4CDYRK1AAURKADAPK3 | |
| SCHEMBL13909686 | 0.68 | KDM5A (0.45) | KDM5AKDM4CDYRK1APIM1DAO | |
| SCHEMBL12215399 | 0.67 | KDM5A (0.51) | KDM5AKDM4CDYRK1ADAPK3ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992392-A | Synthesis of indoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-11-16 | — | — | US | claimed |