Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912051 | 0.87 | ALDH1A1 (0.44) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10687043 | 0.83 | ALDH1A1 (0.51) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11848012 | 0.80 | LIPE (0.48) | LIPEFDFT1MAPTALDH1A1MEN1 | |
| SCHEMBL10689619 | 0.79 | ALDH1A1 (0.42) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3548031 | 0.78 | MEN1 (0.45) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7332808 | 0.78 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL28341780 | 0.77 | LIPE (0.46) | LIPEPOLBFDFT1MAPTALDH1A1 | |
| SCHEMBL28881408 | 0.77 | LIPE (0.46) | LIPEPOLBFDFT1MAPTALDH1A1 | |
| SCHEMBL28341778 | 0.77 | LIPE (0.46) | LIPEPOLBFDFT1MAPTALDH1A1 | |
| SCHEMBL31067226 | 0.76 | LMNA (0.43) | POLBMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997669-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |
| US-3993763-A | ALPHA-(CYCLIC TERTIARY AMINO-PHENYL)-ALIPHATIC ACIDS | CIBA-GEIGY CORPORATION (US) | 1976-11-23 | — | — | US | disclosed |
| US-3936467-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |