Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.62 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.54 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.54 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.46 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848224 | 1.00 | APEX1 (0.62) | APEX1SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11758267 | 0.90 | APEX1 (0.77) | APEX1SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL3410648 | 0.90 | APEX1 (0.77) | APEX1SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL27824530 | 0.81 | APEX1 (0.64) | APEX1SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL10769149 | 0.79 | ENPP2 (0.63) | APEX1SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL12810338 | 0.79 | APEX1 (0.61) | APEX1SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL8654495 | 0.78 | CYP1A2 (0.52) | APEX1ENPP2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8654499 | 0.78 | CYP1A2 (0.52) | APEX1ENPP2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15281245 | 0.78 | APEX1 (0.55) | APEX1SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11758372 | 0.78 | ENPP2 (0.87) | APEX1SUMO2SUMO1SENP7SENP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998957-A | 1,1'-(UREYLENEBIS(SULFO-P-PHENYLENE)BISSULFO-1H,8H-INDAZOLO(2,3,4-CDE)BENZOTRIAZOL-9-IUM HYDROXIDE)INNER SALT | AMERICAN CYANAMID COMPANY (US) | 1976-12-21 | — | — | US | disclosed |