SCHEMBL11845448

SCHEMBL11845448

CCOC(=O)c1cc(NCc2ccccc2)c(Nc2ccccc2)c(S(=O)(=O)Nc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.47
▸ POLB P06746 2/20 0.47
▸ LMNA P02545 5/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ SMN1; SMN2 Q16637 3/20 0.45
▸ HPGD P15428 3/20 0.44
▸ MAPT P10636 5/20 0.43
▸ NAMPT P43490 1/20 0.43
▸ SENP1 Q9P0U3 1/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11843963 0.89 ALOX15 (0.48) ALOX15SMN1; SMN2MAPTNAMPTSENP1
SCHEMBL11841803 0.86 L3MBTL1 (0.50) POLBLMNAHSD17B10HPGDMAPT
SCHEMBL11853481 0.85 MAPT (0.49) ALOX15LMNASMN1; SMN2HPGDMAPT
SCHEMBL11843783 0.84 ALOX15 (0.46) ALOX15POLBLMNASMN1; SMN2MAPT
SCHEMBL11838101 0.83 ALOX15 (0.44) ALOX15SMN1; SMN2MAPTNAMPTSENP1
SCHEMBL11854968 0.83 CISD1 (0.45) ALOX15LMNASMN1; SMN2MAPTNAMPT
SCHEMBL11843685 0.82 MAPT (0.44) ALOX15LMNASMN1; SMN2HPGDMAPT
SCHEMBL11849129 0.81 MAPT (0.46) ALOX15POLBLMNAHSD17B10SMN1; SMN2
SCHEMBL11846270 0.80 ALOX15 (0.44) ALOX15SMN1; SMN2MAPTNAMPTSENP1
SCHEMBL11781708 0.80 MEN1 (0.48) POLBLMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3985777-A Sulphamyl-benzoic acid derivatives LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) 1976-10-12 — — US disclosed
Send feedback