Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11849602 | 0.89 | MAPT (0.51) | MAPTAKR1C3AKR1C2GAAMEN1 | |
| SCHEMBL11847173 | 0.89 | MAPT (0.62) | MAPTAKR1C3AKR1C2HPGDGAA | |
| SCHEMBL11843965 | 0.88 | MAPT (0.51) | MAPTAKR1C3AKR1C2GAAMEN1 | |
| SCHEMBL11836594 | 0.86 | KMT2A (0.46) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL2883308 | 0.86 | HCAR3 (0.55) | MAPTAKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL11783509 | 0.86 | MAPT (0.60) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL11849870 | 0.85 | KMT2A (0.45) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL11850451 | 0.83 | PKM (0.48) | MAPTAKR1C3AKR1C2GAAALDH1A1 | |
| SCHEMBL11848500 | 0.83 | KMT2A (0.50) | MAPTAKR1C3HPGDMEN1KMT2A | |
| SCHEMBL21436556 | 0.82 | VCAM1 (0.50) | MAPTAKR1C3AKR1C2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |