Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846780 | 0.92 | CDC25B (0.41) | CDC25BKDM4EGAAMAPTGFER | |
| SCHEMBL2883310 | 0.91 | KDM4E (0.52) | CDC25BKDM4EGAAMAPTGFER | |
| SCHEMBL11846678 | 0.91 | GAA (0.56) | CDC25BKDM4EGAAMAPTGFER | |
| SCHEMBL11850356 | 0.91 | WDR5 (0.44) | CDC25BKDM4EGAAMAPTGFER | |
| SCHEMBL11780958 | 0.88 | CA1 (0.55) | KDM4EGAAMAPTGFERNPC1 | |
| SCHEMBL11850451 | 0.87 | PKM (0.48) | KDM4EGAAMAPTGFERNPC1 | |
| SCHEMBL11841970 | 0.84 | AKR1C3 (0.45) | KDM4EGAAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL11842798 | 0.82 | NPSR1 (0.44) | CDC25BKDM4EGAAMAPTGFER | |
| SCHEMBL11849602 | 0.80 | MAPT (0.51) | KDM4EGAAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11849822 | 0.79 | AKR1C3 (0.52) | KDM4EGAAMAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |