Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11850140 | 0.88 | CDC25B (0.46) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11778072 | 0.88 | CA1 (0.46) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11783471 | 0.88 | MEN1 (0.53) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11846678 | 0.87 | GAA (0.56) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11846780 | 0.86 | CDC25B (0.41) | CA1CA2CA9CA12MAPT | |
| SCHEMBL2883310 | 0.85 | KDM4E (0.52) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11850356 | 0.85 | WDR5 (0.44) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11850451 | 0.84 | PKM (0.48) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11783509 | 0.82 | MAPT (0.60) | CA1CA2CA9CA12MAPT | |
| SCHEMBL11780330 | 0.82 | MEN1 (0.47) | CA1CA2CA9CA12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |