Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29410646 | 1.00 | HTT (0.47) | HTTALDH1A1RIPK1CYP17A1CYP11B1 | |
| SCHEMBL1183043 | 0.97 | HTT (0.46) | HTTALDH1A1RIPK1CYP17A1CYP11B1 | |
| SCHEMBL8098955 | 0.81 | CYP17A1 (0.56) | HTTALDH1A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL3120224 | 0.80 | DAO (0.44) | HTTALDH1A1RIPK1CYP17A1CYP11B1 | |
| SCHEMBL29447904 | 0.80 | DAO (0.44) | HTTALDH1A1RIPK1CYP17A1CYP11B1 | |
| SCHEMBL23607776 | 0.80 | HTT (0.42) | HTTALDH1A1RIPK1CYP17A1CYP11B1 | |
| SCHEMBL29418197 | 0.80 | CYP1A2 (0.53) | HTTALDH1A1TRPA1TSHRMAOA | |
| SCHEMBL333551 | 0.80 | CYP1A2 (0.53) | HTTALDH1A1TRPA1TSHRMAOA | |
| SCHEMBL2009460 | 0.80 | ALDH1A1 (0.35) | HTTALDH1A1TRPA1TSHRCYP1A2 | |
| SCHEMBL29987766 | 0.80 | ALDH1A1 (0.35) | HTTALDH1A1TRPA1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119465288-A | Anion exchange membrane, preparation method and application thereof, and electrolysis device | 氢和元泰(常州)新材料科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-118063504-A | Fluoro phenyl phosphate compound, perovskite thin film, perovskite solar cell, preparation method, electric equipment and application | 天合光能股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117903168-A | Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof | 南开大学 | 2024-04-19 | — | — | CN | claimed |
| CN-111004228-B | GSK-3 beta/ChE double inhibitor and preparation method and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | claimed |
| CN-112047928-B | Isonicotinamide AChE-GSK3 double inhibitor and preparation method and application thereof | 中国药科大学 | 2022-09-23 | — | — | CN | claimed |
| WO-2021047572-A1 | GSK-3β/CHE DOUBLE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2021-03-18 | — | — | WO | claimed |
| CN-112047928-A | Isonicotinamide AChE-GSK3 double inhibitor and preparation method and application thereof | 中国药科大学 | 2020-12-08 | — | — | CN | claimed |
| CN-111004228-A | GSK-3 β/ChE dual inhibitor and preparation method and application thereof | 中国药科大学 | 2020-04-14 | — | — | CN | claimed |
| US-10590145-B2 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | SHANDONG UNIVERSITY (CN) | 2020-03-17 | — | — | US | claimed |
| US-20200031844-A1 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | SHANDONG UNIVERSITY (CN) | 2020-01-30 | — | — | US | claimed |
| CN-108218896-A | A kind of Thiazolopyrimidine HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-06-29 | — | — | CN | claimed |
| CN-108218890-A | A kind of five yuan of non-aromatic ring miazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-06-29 | — | — | CN | claimed |
| US-20170348258-A1 | 3-Amino Benzamide Derivative Serving As B-Lactam Auxiliary Antibiotic, Preparation Method and Use Thereof | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2017-12-07 | — | — | US | claimed |
| CN-106831814-A | A kind of thieno [3,2 d] RTIs of miazines HIV 1 and its preparation method and application | 山东大学 | 2017-06-13 | — | — | CN | claimed |
| CN-104530078-B | Thieno [3, 2-d] pyrimidine derivative and preparation method and application thereof | 山东大学 | 2017-03-22 | — | — | CN | claimed |
| CN-106117242-A | Tetrahydric thiapyran miazines derivative and preparation method and application | 山东大学 | 2016-11-16 | — | — | CN | claimed |
| CN-105461585-A | 3-aminobenzamide derivative as beta-lactam auxiliary antibiotic, preparation method and application | UNIV HONG KONG POLYTECHNIC | 2016-04-06 | — | — | CN | claimed |
| CN-104530078-A | Thieno [3, 2-d] pyrimidine derivative and preparation method and application thereof | UNIV SHANDONG | 2015-04-22 | — | — | CN | claimed |
| EP-1799677-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | Ranbaxy Laboratories Limited (IN) | 2007-06-27 | — | — | EP | claimed |
| WO-2006038100-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590145-B2 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | TYMP, DPYD, TPMT | HTT 1717/4885ALDH1A1 931/4885RIPK1 2788/4885 |
| US-20170348258-A1 | 3-Amino Benzamide Derivative Serving As B-Lactam Auxiliary Antibiotic, Preparation Method and Use Thereof | BCAT2, SBDS, BCAT1 | HTT 4840/4885ALDH1A1 2169/4885RIPK1 4744/4885 |
| US-20200031844-A1 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | TYMP, DPYD, TPMT | HTT 1717/4885ALDH1A1 931/4885RIPK1 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.