Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 7/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856867 | 0.86 | PIK3CA (0.51) | PIK3CAGBA1PIK3R1MTOR | |
| SCHEMBL11860847 | 0.84 | PIK3CA (0.59) | PIK3CAALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL11857231 | 0.82 | HTR3E (0.53) | PIK3CAALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL11857710 | 0.82 | HTR3E (0.53) | PIK3CAALDH1A1TSHRKDM4EL3MBTL1 | |
| SCHEMBL11859522 | 0.81 | PIK3CA (0.50) | PIK3CAALDH1A1TSHRKDM4EGBA1 | |
| SCHEMBL11856434 | 0.80 | HRH4 (0.63) | PIK3CAALDH1A1KDM4EGBA1 | |
| Hydrochloric Acid SCHEMBL11857285 | 0.79 | HRH4 (0.62) | PIK3CAALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11862975 | 0.79 | PIK3CA (0.54) | PIK3CAALDH1A1TSHRKDM4EL3MBTL1 | |
| Maleic Acid SCHEMBL11850337 | 0.78 | PIK3CA (0.48) | PIK3CAALDH1A1KDM4EPIK3R1MTOR | |
| Fumaric Acid SCHEMBL11850350 | 0.78 | PIK3CA (0.48) | PIK3CAALDH1A1KDM4EPIK3R1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | disclosed |