Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11852069 | 0.99 | ALOX15 (0.49) | ALOX15ALOX12ADRB2ADRB1ADRB3 | |
| SCHEMBL7152345 | 0.85 | ADRB2 (0.54) | ADRB2ADRB1ADRB3SLC2A1KMT2A | |
| SCHEMBL11087208 | 0.85 | ADRB2 (0.54) | ADRB2ADRB1ADRB3SLC2A1KMT2A | |
| SCHEMBL7152349 | 0.85 | ADRB2 (0.54) | ADRB2ADRB1ADRB3SLC2A1KMT2A | |
| Hydrochloric Acid SCHEMBL11084321 | 0.84 | ADRB2 (0.53) | ADRB2ADRB1ADRB3SLC2A1MEN1 | |
| SCHEMBL7148275 | 0.84 | ADRB1 (0.51) | ALOX15ALOX12ADRB2ADRB1ADRB3 | |
| SCHEMBL7148280 | 0.84 | ADRB1 (0.51) | ALOX15ALOX12ADRB2ADRB1ADRB3 | |
| SCHEMBL11088831 | 0.84 | ADRB1 (0.51) | ALOX15ALOX12ADRB2ADRB1ADRB3 | |
| SCHEMBL11849024 | 0.82 | SIGMAR1 (0.48) | ADRB2ADRB1ADRB3KMT2AADRA1A | |
| SCHEMBL11842447 | 0.82 | ADRB2 (0.53) | ADRB2ADRB1ADRB3CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |