Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.39 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533488 | 0.80 | PARP10 (0.35) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11534080 | 0.80 | PARP2 (0.55) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11533095 | 0.75 | PARP10 (0.57) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11536976 | 0.73 | CHEK1 (0.66) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11744096 | 0.73 | PARP2 (0.46) | PARP10PARP2PARP15TNKS2TNKS | |
| Hydrochloric Acid SCHEMBL11747896 | 0.71 | CHEK1 (0.64) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11536264 | 0.70 | PARP10 (0.73) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11532017 | 0.68 | PARP2 (0.53) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL11535039 | 0.68 | BRPF1 (0.39) | PARP10PARP2PARP15TNKS2TNKS | |
| SCHEMBL14054039 | 0.67 | PDE2A (0.45) | LMNAKDM4EALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937713-A | Process for the preparation of s-triazolo[3,4-b]benzothiazoles | ELI LILLY AND COMPANY (US) | 1976-02-10 | — | — | US | claimed |