Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKN1 | Q16512 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163311 | 0.77 | MAPT (0.40) | GABRA1GABRB2MAPTPOLBMEN1 | |
| SCHEMBL11853662 | 0.77 | MAPT (0.35) | GAAPDE4APDE4CPDE4DGABRA1 | |
| SCHEMBL1075197 | 0.76 | NUDT1 (0.44) | GABRA1GABRB2MAPTPOLBMEN1 | |
| SCHEMBL3660175 | 0.76 | GABRA1 (0.46) | GAAGABRA1GABRB2MAPTPOLB | |
| SCHEMBL3658175 | 0.74 | CNR2 (0.40) | GABRA1GABRB2MAPTPOLBNPC1 | |
| SCHEMBL6332531 | 0.73 | PKN1 (0.61) | PKN1PKN2MGAMGAASI | |
| SCHEMBL1984812 | 0.73 | L3MBTL1 (0.48) | GAAGABRA1GABRB2MAPTPOLB | |
| SCHEMBL6403069 | 0.72 | TDP1 (0.49) | PKN1PKN2MGAMGAASI | |
| SCHEMBL18152752 | 0.72 | PKN1 (0.42) | PKN1PKN2MGAMGAASI | |
| SCHEMBL10400677 | 0.71 | MAOB (0.45) | MAPTNPC1LMNARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000295-A | ARACHNICIDAL | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |