Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.42 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332531 | 0.81 | PKN1 (0.61) | TDP1GAAMEN1KMT2AMAPT | |
| SCHEMBL18152752 | 0.79 | PKN1 (0.42) | GAAMEN1POLBKMT2AMAPT | |
| SCHEMBL1013125 | 0.74 | PARP1 (0.59) | TDP1GAAMEN1POLBKMT2A | |
| SCHEMBL3287778 | 0.74 | MEN1 (0.58) | TDP1GAAMEN1POLBKMT2A | |
| SCHEMBL30291834 | 0.74 | MEN1 (0.58) | TDP1GAAMEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL6120896 | 0.73 | PARP1 (0.57) | TDP1GAAMEN1POLBKMT2A | |
| SCHEMBL6403073 | 0.72 | TYMS (0.38) | TDP1MEN1POLBKMT2AMAPT | |
| SCHEMBL15323237 | 0.71 | PLAUR (0.58) | TDP1GAAMEN1POLBKMT2A | |
| SCHEMBL30132368 | 0.71 | PKN1 (0.58) | TDP1GAAMEN1KMT2AMAPT | |
| SCHEMBL837903 | 0.71 | PKN1 (0.58) | TDP1GAAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277686-A1 | Benzimidazole compounds for regulating IgE | SIRCAR JAGADISH C | 2005-12-15 | — | — | US | disclosed |
| US-20050197375-A1 | Use of benzimidazole analogs in the treatment of cell proliferation | AVANIR PHARMACEUTICALS | 2005-09-08 | — | — | US | disclosed |
| US-6911462-B2 | Benzimidazole compounds for regulating IgE | AVANIR PHARMACEUTICALS (US) | 2005-06-28 | — | — | US | disclosed |
| US-20030100582-A1 | Benzimidazole compounds for regulating IgE | AVANIR PHARMACEUTICALS | 2003-05-29 | — | — | US | disclosed |
| US-4284713-A | SILVER, SILVER HALIDE OR BINDER IMAGE, MASKING, EXPOSURE, DEVELOPMENT, DECOMPOSITION, ALKALI HALATE OR HALITE, ETCHING | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| US-4254214-A | BLACK, REDUCTION OF COPPER SALT OR COMPLEX TO COPPER | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4021247-A | Method of dispersing organic compounds useful in photography | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100582-A1 | Benzimidazole compounds for regulating IgE | FCER2, SERPINB1, BRPF3 | TDP1 3968/4885GAA 1554/4885MEN1 4827/4885 |
| US-20050277686-A1 | Benzimidazole compounds for regulating IgE | FCER2, SERPINB1, BRPF3 | TDP1 3968/4885GAA 1554/4885MEN1 4827/4885 |
| US-20050197375-A1 | Use of benzimidazole analogs in the treatment of cell proliferation | MKI67, CCNI, CDKN1A | TDP1 2445/4885GAA 1414/4885MEN1 2358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.