SCHEMBL11854343

SCHEMBL11854343

CCCC(=O)OCCN(CCOC(=O)CCC)c1ccc(C=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
ALDH3A1 P30838 1/20 0.51
ALDH1A3 P47895 1/20 0.51
CDYL Q9Y232 1/20 0.40
KDM4E B2RXH2 4/20 0.40
GAA P10253 2/20 0.40
MAPT P10636 4/20 0.39
HPGD P15428 2/20 0.39
GLA P06280 1/20 0.39
GFER P55789 1/20 0.39
KMT2A Q03164 2/20 0.39
CYP2A6 P11509 1/20 0.39
CYP2A13 Q16696 1/20 0.39
DNM1 Q05193 1/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 2/20 0.37
MEN1 O00255 1/20 0.36
ESRRG P62508 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9331718 0.82 SMN1; SMN2 (0.51) ALDH1A1CDYLKDM4EMAPTKMT2A
SCHEMBL7987478 0.82 ALDH1A1 (0.53) ALDH1A1ALDH3A1ALDH1A3KDM4EGAA
SCHEMBL11695333 0.81 ALDH1A1 (0.49) ALDH1A1ALDH3A1ALDH1A3KDM4EGAA
SCHEMBL11652998 0.79 SMN1; SMN2 (0.49) ALDH1A1CDYLKDM4EGAAMAPT
SCHEMBL5689109 0.79 ALDH1A1 (0.59) ALDH1A1ALDH3A1ALDH1A3KDM4EGAA
SCHEMBL11698911 0.79 ALDH1A1 (0.44) ALDH1A1ALDH3A1ALDH1A3KDM4EGAA
SCHEMBL9915608 0.78 DNM1 (0.52) ALDH1A1KDM4EGAAMAPTHPGD
SCHEMBL8501459 0.77 ALDH1A1 (0.51) ALDH1A1ALDH3A1ALDH1A3KDM4EMAPT
SCHEMBL13144571 0.77 ALDH1A1 (0.44) ALDH1A1ALDH3A1ALDH1A3KDM4EGAA
SCHEMBL1607796 0.76 ALDH3A1 (0.73) ALDH1A1ALDH3A1ALDH1A3KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3962220-A ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed
US-3962221-A CONDENSATION, REDUCTION, OXIDATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed