Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 7/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625184 | 0.88 | MLYCD (0.38) | MLYCDNR1H4CYP2C9HDAC1HDAC8 | |
| SCHEMBL11679589 | 0.86 | PGR (0.38) | MLYCDPGRARNR1H4CYP2C9 | |
| SCHEMBL27625178 | 0.85 | MLYCD (0.36) | MLYCDNR1H4CYP2C9HDAC1HDAC8 | |
| SCHEMBL12632153 | 0.83 | CYP2C9 (0.50) | CYP2C9HDAC1USP5ALDH1A1SMN1; SMN2 | |
| SCHEMBL15853339 | 0.82 | HDAC1 (0.40) | MLYCDPGRARNR1H4CYP2C9 | |
| SCHEMBL12672617 | 0.80 | PGR (0.37) | MLYCDPGRARNR1H4CYP2C9 | |
| SCHEMBL10031827 | 0.80 | PGR (0.47) | MLYCDPGRARHDAC1ELANE | |
| SCHEMBL11855770 | 0.78 | NR1H4 (0.54) | NR1H4CYP2C9ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13760252 | 0.77 | PGR (0.36) | MLYCDPGRARNR1H4CYP2C9 | |
| SCHEMBL28516564 | 0.77 | ABCB11 (0.38) | MLYCDPGRARNR1H4USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996286-A | HYPOLIPIDEMIC AGENTS, HYPOCHOLESTEROLEMICS | SANDOZ, INC. (US) | 1976-12-07 | — | — | US | disclosed |