SCHEMBL118557

SCHEMBL118557

Oc1ccc(C(O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.55
ESR2 Q92731 8/20 0.55
PDCD1 Q15116 1/20 0.55
CD274 Q9NZQ7 1/20 0.55
HIF1A Q16665 3/20 0.53
ALOX15 P16050 3/20 0.53
KDM4E B2RXH2 3/20 0.53
CYP3A4 P08684 3/20 0.53
NFKB1 P19838 2/20 0.53
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.53
ALDH1A1 P00352 2/20 0.53
THPO P40225 2/20 0.53
BLM P54132 2/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
CA12 O43570 1/20 0.53
GMNN O75496 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556561 0.91 ESR1 (0.61) ESR1ESR2PDCD1CD274HIF1A
SCHEMBL2376299 0.86 ESR1 (0.35) ESR1ESR2PDCD1CD274HIF1A
SCHEMBL10445959 0.84 ESR1 (0.67) ESR1ESR2PDCD1CD274HIF1A
SCHEMBL3649813 0.80 ESR1 (0.55) ESR1ESR2PDCD1CD274HIF1A
Bis(4-Hydroxyphenyl)Methanol SCHEMBL3642317 0.80 CYP3A4 (0.62) ESR1ESR2PDCD1CD274HIF1A
Phenol SCHEMBL28221659 0.79 CA12 (0.61) ESR1ESR2HIF1AKDM4ELMNA
SCHEMBL31274990 0.76 ESR1 (0.58) ESR1ESR2PDCD1CD274HIF1A
SCHEMBL216712 0.76 ESR1 (0.58) ESR1ESR2PDCD1CD274HIF1A
SCHEMBL40254 0.76 ESR1 (0.58) ESR1ESR2PDCD1CD274HIF1A
SCHEMBL133408 0.76 ESR1 (0.58) ESR1ESR2PDCD1CD274HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702075-A1 A MODIFIED CURING AGENT COMPONENT AND A PROCESS FOR PREPARING THE SAME Grasim Industries Limited (IN) 2026-03-04 EP claimed
WO-2024224303-A1 A MODIFIED CURING AGENT COMPONENT AND A PROCESS FOR PREPARING THE SAME GRASIM INDUSTRIES LIMITED (IN) 2024-10-31 WO claimed
CN-118136842-A Negative electrode material and preparation method and application thereof 湖南中科星城石墨有限公司 2024-06-04 CN claimed
CN-117466277-A Hard carbon precursor, hard carbon, preparation method of hard carbon and sodium battery 湖南中科星城石墨有限公司 2024-01-30 CN claimed
CN-115969807-B Soft capsule content containing bioactive components and its preparation method 青岛双鲸药业股份有限公司 2023-09-19 CN claimed
CN-115969807-A Soft capsule content containing bioactive components and preparation method thereof 青岛双鲸药业股份有限公司 2023-04-18 CN claimed
CN-111253361-B Preparation method of 3, 4-methylenedioxyphenol 苏州敬业医药化工有限公司 2022-03-15 CN claimed
CN-111777953-B Thread locking anaerobic adhesive and preparation method thereof 黑龙江省科学院石油化学研究院 2021-10-29 CN claimed
US-20210078941-A1 Method For Preparing Substituted Phenylacetic Acid Derivative JIANGSU RUIKE MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) 2021-03-18 US claimed
EP-3680227-A1 METHOD FOR PREPARING SUBSTITUTED PHENYLACETIC ACID DERIVATIVE Jiangsu Ruike Medical Science And Technology Co., Ltd. (CN) 2020-07-15 EP claimed
US-5679766-A Purification process of novolar resins using acid treated chelating cation exchange resin SHIPLEY COMPANY, L.L.C. (US) 1997-10-21 US claimed
US-5648196-A Water-soluble photoinitiators CORNELL RESEARCH FOUNDATION, INC. (US) 1997-07-15 US claimed
US-5597876-A CURING AGENT PROVIDES BETTER MECHANICAL PROPERTIES AT HIGH TEMPERATURE SHELL OIL COMPANY (US) 1997-01-28 US claimed
EP-0663814-A1 PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR L'OREAL (FR) 1995-07-26 EP claimed
US-5238776-A Improved thermal properties, etch resistance, high speed SHIPLEY COMPANY INC. (US) 1993-08-24 US claimed
WO-1993010744-A2 PROCESS FOR DYEING KERATIN FIBRES USING AN ACID PH ALCOXYMETEPHENYLENEDIAMINE AND COMPOSITIONS THEREFOR L'OREAL (FR) 1993-06-10 WO claimed
US-5130410-A Condencing a bishydroxymethyl phenol with a reactive phenol in the absence of an aldehyde to form an alternating copolymer and reacting in the presence of an aromatic aldehyde SHIPLEY COMPANY INC. (US) 1992-07-14 US claimed
EP-0400330-A1 Oxidation hair dyes Wella Aktiengesellschaft (DE) 1990-12-05 EP claimed
EP-0105009-B1 METHOD OF PREPARING FOAMS BY CONDENSING METHYLOLDIHYDROXIDEPHENYL ETHER; THEIR APPLICATION AS AN ISOLATION MATERIAL SADEV - SOCIETE D'APPLICATION ET DE DEVELOPPEMENT DE TECHNIQUES NOUVELLES (FR) 1986-03-26 EP claimed
EP-0000165-B1 PROCESS FOR PREPARING PURE 2-HYDROXYBENZYL ALCOHOL AND PURE 4-HYDROXYBENZYL ALCOHOL OR A MIXTURE OF BOTH HYDROXYBENZYL ALCOHOLS HAARMANN & REIMER GMBH (DE) 1981-06-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210078941-A1 Method For Preparing Substituted Phenylacetic Acid Derivative ALOX5, LOXL4, CYP3A5 ESR1 1084/4885ESR2 1176/4885PDCD1 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.