SCHEMBL11858843

SCHEMBL11858843

CCCCc1cccc(CCCC)c1N=CNC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.50
CYP2D6 P10635 5/20 0.50
CYP2C9 P11712 5/20 0.50
LIPG Q9Y5X9 1/20 0.35
ALOX5 P09917 1/20 0.35
PTGS2 P35354 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
CYP4Z1 Q86W10 1/20 0.34
CYP4F11 Q9HBI6 1/20 0.34
CYP4F12 Q9HCS2 1/20 0.34
BID P55957 4/20 0.33
MCL1 Q07820 4/20 0.33
BCL2L1 Q07817 3/20 0.33
BAK1 Q16611 3/20 0.33
KAT8 Q9H7Z6 2/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
EP300 Q09472 1/20 0.33
KAT2A Q92830 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30102447 0.77 LIPG (0.46) CYP3A4CYP2D6CYP2C9LIPGALOX5
SCHEMBL21765894 0.74 GABRA1 (0.36) CYP3A4CYP2D6CYP2C9ALOX5PTGS2
Hydrochloric Acid SCHEMBL7176130 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9LIPGALOX5
Hydrochloric Acid SCHEMBL7178593 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9LIPGALOX5
Hydrochloric Acid SCHEMBL7177087 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9LIPGALOX5
Hydrochloric Acid SCHEMBL7171152 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9LIPGALOX5
Hydrochloric Acid SCHEMBL7175801 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9LIPGALOX5
Hydrochloric Acid SCHEMBL7181337 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9LIPGALOX5
Hydrochloric Acid SCHEMBL7181600 0.71 CYP3A4 (0.39) CYP3A4CYP2D6CYP2C9LIPGALOX5
SCHEMBL18245197 0.71 GABRA1 (0.47) CYP3A4CYP2D6CYP2C9LIPGALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3954997-A MITICIDES, INSECTICIDES THE UPJOHN COMPANY (US) 1976-05-04 US disclosed