Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 6/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765894 | 0.86 | GABRA1 (0.36) | ALOX5PTGS2F7F3MMP2 | |
| SCHEMBL14321647 | 0.77 | LIPG (0.46) | LIPGALOX5PTGS2SAE1BID | |
| SCHEMBL11858843 | 0.77 | CYP3A4 (0.50) | LIPGALOX5PTGS2SAE1BID | |
| SCHEMBL30037094 | 0.74 | LIPG (0.65) | LIPGALOX5PTGS2SAE1MAPT | |
| SCHEMBL82794 | 0.74 | LIPG (0.65) | LIPGALOX5PTGS2SAE1MAPT | |
| SCHEMBL1193690 | 0.74 | KCNH2 (0.50) | LIPGALOX5PTGS2SAE1BID | |
| SCHEMBL21765629 | 0.73 | CYP3A4 (0.68) | LIPGALOX5PTGS2F7F3 | |
| SCHEMBL861958 | 0.73 | LIPG (0.53) | LIPGALOX5PTGS2SAE1BID | |
| SCHEMBL200263 | 0.72 | LIPG (0.48) | LIPGALOX5PTGS2SAE1BID | |
| SCHEMBL677510 | 0.72 | LIPG (0.48) | LIPGALOX5PTGS2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818545-B | Method for preparing substituted aryl ketone by ketone arylation | 上海化工研究院有限公司 | 2022-12-09 | — | — | CN | disclosed |