Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 7/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101512 | 0.79 | HPGD (0.47) | KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL12935252 | 0.74 | MAPT (0.40) | KDM4ETDP1MAPTHTTSMN1; SMN2 | |
| Perchlorate SCHEMBL2057139 | 0.74 | HPGD (0.42) | KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL17532457 | 0.70 | ALDH1A1 (0.77) | ALDH1A1LMNAKDM4ERAB9ATDP1 | |
| SCHEMBL12934729 | 0.70 | HPGD (0.52) | ALDH1A1LMNAKDM4ERAB9AMAPT | |
| SCHEMBL4754788 | 0.69 | MEN1 (0.41) | RAB9ATDP1NPSR1 | |
| SCHEMBL11845646 | 0.68 | BACE1 (0.41) | HTT | |
| SCHEMBL8390740 | 0.67 | CA2 (0.40) | ALDH1A1LMNAKDM4ERAB9APDE4B | |
| SCHEMBL2005219 | 0.67 | GAA (0.41) | ALDH1A1LMNAKDM4ETDP1HSD17B10 | |
| SCHEMBL8390737 | 0.66 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |