Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL2057139 | 0.93 | HPGD (0.42) | HPGDMAPTPABPC1ALOX15MAPK1 | |
| SCHEMBL12935252 | 0.92 | MAPT (0.40) | HPGDMAPTPABPC1ALOX15MAPK1 | |
| SCHEMBL8927286 | 0.81 | PGR (0.34) | KMT2AMEN1 | |
| SCHEMBL11848984 | 0.81 | TGM2 (0.44) | HPGDMAPTPABPC1ALOX15MAPK1 | |
| SCHEMBL12934729 | 0.79 | HPGD (0.52) | HPGDMAPTMAPK1KMT2APKM | |
| SCHEMBL11858905 | 0.79 | ALDH1A1 (0.47) | MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL11857466 | 0.79 | MAPT (0.40) | MAPTALOX15HTTKMT2APKM | |
| SCHEMBL2057331 | 0.73 | ALOX15 (0.46) | HPGDMAPTPABPC1ALOX15MAPK1 | |
| SCHEMBL13984874 | 0.72 | MEN1 (0.34) | KMT2AMEN1CASP3 | |
| SCHEMBL9757294 | 0.71 | MAPT (0.58) | HPGDMAPTPABPC1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186870-B2 | FRET-labeled compounds and uses therefor | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-20200318178-A1 | FRET-LABELED COMPOUNDS AND USES THEREFOR | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2020-10-08 | — | — | US | disclosed |
| US-10570445-B2 | Fret-labeled compounds and uses therefor | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20190032117-A1 | FRET-LABELED COMPOUNDS AND USES THEREFOR | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2019-01-31 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-9777320-B2 | Molecular adaptors for dye conjugates | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20170239377-A1 | MOLECULAR PROBES FOR MULTIMODALITY IMAGING AND TRACKING OF STEM CELLS | UNIV MASSACHUSETTS (US) | 2017-08-24 | — | — | US | disclosed |
| US-20070021621-A1 | Water soluble fluorescent compounds | BIOSEARCH TECHNOLOGIES, INC. (US) | 2007-01-25 | — | — | US | disclosed |
| EP-1322664-B1 | DYE-LABELLED PEPTIDE AND ITS DIAGNOSTIC USE | GE HEALTHCARE UK LTD (GB) | 2006-07-12 | — | — | EP | disclosed |
| US-6686145-B1 | IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS BY COVALENT AND NONCOVALENT ASSOCIATION | CARNEGIE MELLON UNIVERSITY | 2004-02-03 | — | — | US | disclosed |
| US-20040018579-A1 | Dye-labelled peptide and method | GE HEALTHCARE UK LIMITED (GB) | 2004-01-29 | — | — | US | disclosed |
| US-20030224391-A1 | Rigidized trimethine cyanine dyes | CARNEGIE MELLON UNIVERSITY | 2003-12-04 | — | — | US | disclosed |
| EP-1042407-B1 | RIGIDIZED TRIMETHINE CYANINE DYES | UNIV CARNEGIE MELLON (US) | 2001-09-12 | — | — | EP | disclosed |
| US-6133445-A | USEFUL FOR IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS | CARNEGIE MELLON UNIVERSITY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1042407-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE-MELLON UNIVERSITY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031181-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE MELLON UNIVERSITY (US) | 1999-06-24 | — | — | WO | disclosed |
| US-3975379-A | METHINE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11186870-B2 | FRET-labeled compounds and uses therefor | METTL16, TARBP1, RNGTT | HPGD 1970/4885MAPT 3652/4885PABPC1 155/4885 |
| US-10570445-B2 | Fret-labeled compounds and uses therefor | METTL16, TARBP1, RNGTT | HPGD 1970/4885MAPT 3652/4885PABPC1 155/4885 |
| US-20190032117-A1 | FRET-LABELED COMPOUNDS AND USES THEREFOR | METTL16, TARBP1, RNGTT | HPGD 1970/4885MAPT 3652/4885PABPC1 155/4885 |
| US-20030224391-A1 | Rigidized trimethine cyanine dyes | CBR1, TH, CBR3 | HPGD 4367/4885MAPT 4395/4885PABPC1 3702/4885 |
| US-20070021621-A1 | Water soluble fluorescent compounds | ABCG2, AQP1, AQP3 | HPGD 2025/4885MAPT 523/4885PABPC1 4361/4885 |
| US-20040018579-A1 | Dye-labelled peptide and method | VIP, IAPP, NGLY1 | HPGD 1620/4885MAPT 2148/4885PABPC1 3380/4885 |
| US-20170239377-A1 | MOLECULAR PROBES FOR MULTIMODALITY IMAGING AND TRACKING OF STEM CELLS | CD44, FABP3, FABP7 | HPGD 3646/4885MAPT 1775/4885PABPC1 2016/4885 |
| US-20200318178-A1 | FRET-LABELED COMPOUNDS AND USES THEREFOR | METTL16, TARBP1, RNGTT | HPGD 1970/4885MAPT 3652/4885PABPC1 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.