Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390740 | 0.88 | CA2 (0.40) | KDM4EHPGDMAPTNFKB1LMNA | |
| SCHEMBL8390737 | 0.87 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL14048572 | 0.85 | CYP26B1 (0.46) | CYP26A1CYP26B1 | |
| SCHEMBL8328904 | 0.84 | ALDH1A1 (0.44) | GAAKDM4EHPGDMAPTTSHR | |
| SCHEMBL18386310 | 0.83 | SMN1; SMN2 (0.42) | MAPTNFKB1LMNAMEN1KMT2A | |
| SCHEMBL28870507 | 0.76 | TDP1 (0.41) | GAATDP1BLMRXRARXRB | |
| SCHEMBL29367860 | 0.76 | TDP1 (0.41) | GAATDP1BLMRXRARXRB | |
| SCHEMBL2066598 | 0.76 | CA5A (0.35) | GAAKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL5556297 | 0.73 | GRIN2D (0.33) | — | |
| SCHEMBL5851116 | 0.73 | SKP2 (0.41) | KDM4EHSD17B10LMNAHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260053393-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA INC (US) | 2026-02-26 | — | — | US | disclosed |
| US-20250230174-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2025-07-17 | — | — | US | disclosed |
| US-12285250-B2 | Near-IR glucose sensors | PROFUSA, INC (US) | 2025-04-29 | — | — | US | disclosed |
| EP-3309552-B1 | DYE COMPOUND | SFC CO LTD (KR) | 2024-01-17 | — | — | EP | disclosed |
| EP-3813667-A1 | NEAR-IR GLUCOSE SENSORS | Profusa, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2021-04-08 | — | — | US | disclosed |
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | PROFUSA, INC. (US) | 2021-04-08 | — | — | US | disclosed |
| CN-112601491-A | Near-infrared glucose sensor | 普罗菲尤萨股份有限公司 | 2021-04-02 | — | — | CN | disclosed |
| US-10717751-B2 | Near-IR glucose sensors | PROFUSA, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-10717751-B2 | Near-IR glucose sensors | PROFUSA, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| EP-1252520-A2 | METHODS EMPLOYING INCREASED DYE-FLUORESCENCE UPON NITROREDUCTION | Amersham Biosciences UK Limited (GB) | 2002-10-30 | — | — | EP | disclosed |
| EP-1212375-A2 | PH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS | CARNEGIE-MELLON UNIVERSITY (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000075237-A9 | pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS | UNIV CARNEGIE MELLON (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002029407-A2 | DYE-LABELLED PEPTIDE AND ITS DIAGNOSTIC USE | AMERSHAM BIOSCIENCES UK LTD. (GB) | 2002-04-11 | — | — | WO | disclosed |
| EP-1042407-B1 | RIGIDIZED TRIMETHINE CYANINE DYES | UNIV CARNEGIE MELLON (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001057237-A2 | METHODS EMPLOYING INCREASED DYE-FLUORESCENCE UPON NITROREDUCTION | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2001-08-09 | — | — | WO | disclosed |
| WO-2000075237-A2 | pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS | CARNEGIE MELLON UNIVERSITY (US) | 2000-12-14 | — | — | WO | disclosed |
| US-6133445-A | USEFUL FOR IMPARTING FLUORESCENT PROPERTIES TO TARGET MATERIALS | CARNEGIE MELLON UNIVERSITY (US) | 2000-10-17 | — | — | US | disclosed |
| EP-1042407-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE-MELLON UNIVERSITY (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031181-A1 | RIGIDIZED TRIMETHINE CYANINE DYES | CARNEGIE MELLON UNIVERSITY (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250230174-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | GAA 155/4885KDM4E 3160/4885HPGD 3387/4885 |
| US-20210101915-A1 | NEAR-IR GLUCOSE SENSORS | IRS1, INSR, SLC2A4 | GAA 155/4885KDM4E 3160/4885HPGD 3387/4885 |
| US-20260053393-A1 | NEAR-IR GLUCOSE SENSORS | INSR, IRS1, SLC2A4 | GAA 2580/4885KDM4E 3774/4885HPGD 4462/4885 |
| US-12285250-B2 | Near-IR glucose sensors | IRS1, SLC2A4, GPR119 | GAA 182/4885KDM4E 1818/4885HPGD 2318/4885 |
| US-10717751-B2 | Near-IR glucose sensors | IRS1, G6PD, SLC2A8 | GAA 55/4885KDM4E 1515/4885HPGD 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.