Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.55 |
| ▸ | CA1 | P00915 | 14/20 | 0.53 |
| ▸ | CA12 | O43570 | 12/20 | 0.53 |
| ▸ | CA9 | Q16790 | 15/20 | 0.50 |
| ▸ | CA7 | P43166 | 9/20 | 0.50 |
| ▸ | CA5A | P35218 | 8/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.50 |
| ▸ | CA6 | P23280 | 5/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3430584 | 0.80 | CA2 (0.52) | CA2CA1CA12CA9CA7 | |
| SCHEMBL11020793 | 0.77 | TSHR (0.52) | CYP2C19KMT2ATSHRTDP1MEN1 | |
| SCHEMBL18955144 | 0.76 | CA2 (0.55) | CA2CA1CA12CA9CA7 | |
| SCHEMBL202948 | 0.74 | CA2 (0.81) | CA2CA1CA12CA9CA7 | |
| SCHEMBL27587941 | 0.73 | HTR6 (0.52) | CYP2C19KMT2ATSHRTDP1MEN1 | |
| SCHEMBL65464 | 0.73 | ALDH1A1 (0.44) | CA14CA6CA3CYP2C19KMT2A | |
| SCHEMBL11417635 | 0.73 | ESR1 (0.43) | CA2CA1CA12CA9CA7 | |
| SCHEMBL4587677 | 0.71 | NPC1 (0.45) | CA2CA1CYP2C19TSHRTDP1 | |
| SCHEMBL5808336 | 0.71 | KCNN4 (0.45) | CA2CA1TSHR | |
| SCHEMBL176891 | 0.71 | CA2 (1.00) | CA2CA1CA12CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931202-A | Pyridyl phenyl-carbamate rodenticides | ROHM AND HAAS COMPANY (US) | 1976-01-06 | — | — | US | disclosed |