Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853403 | 0.77 | CYP3A4 (0.42) | LMNAGAADCTPP1CYP3A4TSHR | |
| SCHEMBL11684355 | 0.70 | TXNRD1 (0.40) | LMNADCTPP1CYP3A4TSHRMAPK1 | |
| SCHEMBL8855627 | 0.70 | CYP3A4 (0.43) | LMNAGAADCTPP1CYP3A4TSHR | |
| SCHEMBL11863501 | 0.70 | CYP3A4 (0.40) | LMNAGAADCTPP1CYP3A4TSHR | |
| SCHEMBL11643945 | 0.68 | DCTPP1 (0.34) | DCTPP1 | |
| SCHEMBL11854918 | 0.67 | PLK1 (0.41) | LMNAGAADCTPP1CYP3A4TSHR | |
| SCHEMBL8855447 | 0.66 | CYP3A4 (0.39) | LMNAGAACYP3A4TSHRMAPK1 | |
| SCHEMBL8855433 | 0.65 | MAPT (0.40) | LMNAGAADCTPP1CYP3A4TSHR | |
| SCHEMBL8855527 | 0.64 | CYP3A4 (0.41) | LMNAGAADCTPP1CYP3A4TSHR | |
| SCHEMBL11685455 | 0.63 | CREBBP (0.45) | LMNADCTPP1TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |