Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855525 | 0.86 | PLK1 (0.53) | TXNRD1TXNRD3TXNRD2DCTPP1PLK1 | |
| SCHEMBL11683669 | 0.85 | ALDH1A1 (0.40) | CREBBPTXNRD1TXNRD3TXNRD2DCTPP1 | |
| SCHEMBL11684355 | 0.80 | TXNRD1 (0.40) | CREBBPTXNRD1TXNRD3TXNRD2DCTPP1 | |
| SCHEMBL8855422 | 0.77 | PLK1 (0.50) | TXNRD1TXNRD3TXNRD2DCTPP1PLK1 | |
| SCHEMBL8733239 | 0.76 | PLK1 (0.48) | TXNRD1TXNRD3TXNRD2DCTPP1PLK1 | |
| SCHEMBL11629785 | 0.75 | ALDH1A1 (0.42) | CREBBPPLK1MAPTMAPK1ALDH1A1 | |
| SCHEMBL11854099 | 0.73 | DCTPP1 (0.35) | TXNRD1TXNRD3TXNRD2DCTPP1PLK1 | |
| SCHEMBL11860634 | 0.71 | PLK1 (0.39) | TXNRD1TXNRD3TXNRD2DCTPP1PLK1 | |
| SCHEMBL22954616 | 0.69 | PLK1 (0.50) | TXNRD1TXNRD3TXNRD2PLK1MAPT | |
| SCHEMBL29517736 | 0.69 | PLK1 (0.50) | TXNRD1TXNRD3TXNRD2PLK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031107-A | Method for introducing amino groups into benzimidazole or imidazopyridine compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | disclosed |