Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASR | P41180 | 5/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160051 | 0.85 | CASR (0.59) | MAPTTP53CASRPTGDR2NPSR1 | |
| SCHEMBL11864694 | 0.82 | MAPT (0.44) | MAPTTP53CASRMTNR1AMTNR1B | |
| SCHEMBL11159700 | 0.79 | USP2 (0.42) | TP53CASRMEN1KMT2ALMNA | |
| SCHEMBL11870272 | 0.79 | ALDH1A1 (0.46) | MAPTCASRMEN1KMT2APTGDR2 | |
| SCHEMBL11158937 | 0.79 | CASR (0.57) | MAPTTP53CASRPTGDR2NPSR1 | |
| SCHEMBL11164228 | 0.77 | CASR (0.57) | MAPTTP53CASRKMT2ANPSR1 | |
| SCHEMBL11468901 | 0.76 | CASR (0.51) | MAPTTP53CASRPTGDR2LMNA | |
| SCHEMBL11869979 | 0.76 | CASR (0.42) | MAPTCASRPTGDR2POLBNPSR1 | |
| SCHEMBL11469861 | 0.75 | CASR (0.55) | MAPTTP53CASRPTGDR2NPSR1 | |
| SCHEMBL11467140 | 0.74 | CASR (0.50) | MAPTTP53CASRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |