Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GSDMD | P57764 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353548 | 0.86 | ABCB11 (0.40) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL11863639 | 0.85 | ALDH1A1 (0.33) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL992706 | 0.76 | TDP1 (0.33) | ALDH1A1 | |
| SCHEMBL9763736 | 0.76 | TDP1 (0.33) | — | |
| SCHEMBL5958509 | 0.76 | CA12 (0.46) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL11866881 | 0.74 | ABCB11 (0.30) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL599215 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL15655347 | 0.72 | ZDHHC20 (0.42) | — | |
| SCHEMBL24176571 | 0.71 | TDP1 (0.30) | — | |
| SCHEMBL7177610 | 0.71 | ABCB11 (0.35) | ABCB11CYP2E1PTGS1HTTGSDMD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957718-A | Compositions containing silica, a phenoplast or an aminoplast, and a silane | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1976-05-18 | — | — | US | disclosed |