Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GSDMD | P57764 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862872 | 0.86 | ABCB11 (0.32) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL11866881 | 0.84 | ABCB11 (0.30) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL599215 | 0.81 | ALDH1A1 (0.31) | ALDH1A1ALDH2 | |
| SCHEMBL11863504 | 0.80 | CA12 (0.42) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL11866704 | 0.80 | ABCB11 (0.48) | ABCB11CYP2E1PTGS1HTTGSDMD | |
| SCHEMBL20982037 | 0.77 | POLB (0.40) | ALDH1A1 | |
| SCHEMBL2565127 | 0.77 | CA12 (0.32) | ALDH1A1 | |
| SCHEMBL19983357 | 0.76 | CA12 (0.31) | — | |
| SCHEMBL4359796 | 0.74 | CA12 (0.31) | — | |
| SCHEMBL442777 | 0.74 | ALOX15 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348620-B1 | Process for the preparation of mono- or polysubstituted organyloxysilyl-functional thiourea, and these compounds | DEGUSSA (DE) | 1994-08-31 | — | — | EP | disclosed |