Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 5/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.42 |
| ▸ | PIK3R5 | Q8WYR1 | 5/20 | 0.42 |
| ▸ | PIK3R3 | Q92569 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865791 | 0.92 | CNR2 (0.47) | CNR1CNR2RAD52 | |
| SCHEMBL11870415 | 0.91 | CNR2 (0.49) | CNR1CNR2RAD52 | |
| SCHEMBL11859783 | 0.91 | RAD52 (0.44) | KDM4ETP53CNR1CNR2RAD52 | |
| SCHEMBL11863304 | 0.85 | ABCB1 (0.59) | ABCB1KDM4ETSHRCNR1CNR2 | |
| SCHEMBL11859533 | 0.81 | RAD52 (0.47) | KDM4ETP53CNR1CNR2RAD52 | |
| SCHEMBL11864104 | 0.81 | RAD52 (0.57) | KDM4ETP53CNR1CNR2RAD52 | |
| Hydrochloric Acid SCHEMBL11861513 | 0.80 | RAD52 (0.57) | KDM4ETP53TSHRCNR1CNR2 | |
| SCHEMBL11863026 | 0.79 | KMT2A (0.53) | CNR1CNR2RAD52GAAALDH1A1 | |
| SCHEMBL5698605 | 0.78 | CNR2 (0.51) | KDM4ECNR1CNR2RAD52ALDH1A1 | |
| SCHEMBL11870710 | 0.77 | CNR2 (0.54) | ABCB1CNR1CNR2RAD52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |